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For example, in the case of cigarettes, over 60 years of detailed scientific work undertaken to elucidate the chemical composition of both tobacco and smoke have highlighted their extreme chemical complexity at over 8,000 identified compounds in tobacco and over 6,500 identified compounds in cigarette smoke ( The growth in e-cigarette use as an alternative to cigarette smoking has led to significant efforts to understand the chemical composition of both e-liquids and e-cigarette aerosols

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